Search results for " CNP"

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Natriuretic peptide system expression in murine and human submandibular salivary glands: a study of the spatial localisation of ANB, BNP, CNP and the…

2019

AbstractThe natriuretic peptide (NP) system comprises of three ligands, the Atrial Natriuretic Peptide (ANP), Brain Natriuretic peptide (BNP) and C-type Natriuretic peptide (CNP), and three natriuretic peptide receptors, NPRA, NPRB and NPRC. Here we present a comprehensive study of the natriuretic peptide system in healthy murine and human submandibular salivary glands (SMGs). We show CNP is the dominant NP in mouse and human SMG and is expressed together with NP receptors in ducts, autonomic nerves and the microvasculature of the gland, suggesting CNP autocrine signalling may take place in some of these glandular structures. These data suggest the NP system may control salivary gland funct…

MaleSettore BIO/17 - Istologia0301 basic medicinemedicine.medical_specialtyHistologyReceptors PeptidePhysiologymedicine.drug_classAtrial natriuretic peptide ANPNatriuretic peptide receptor B NPRBMice03 medical and health sciences0302 clinical medicineAtrial natriuretic peptideInternal medicineNatriuretic Peptide BrainmedicineNatriuretic peptideAnimalsHumansAutonomic nervous systemB-type natriuretic peptide BNPNatriuretic peptide receptor C NPRCAutocrine signallingReceptorSalivary glandSubmandibular glandSalivary glandC-type natriuretic peptide CNPChemistryNatriuretic Peptide C-TypeCell BiologyGeneral MedicineNatriuretic peptide receptor A NPRABrain natriuretic peptideSubmandibular glandNeoplasm Proteins030104 developmental biologymedicine.anatomical_structureEndocrinologyOral squamous cell carcinoma030220 oncology & carcinogenesisCarcinoma Squamous CellFemaleMouth NeoplasmsAtrial Natriuretic FactorHomeostasisJournal of Molecular Histology
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